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BIO201 - Microbiology and Human Disease
Catalog Description: Studies the characteristics of microorganisms, their role in health and disease, and methods of controlling them. Examines mechanisms of immunity. Laboratory exercises reinforce important concepts and aseptic techniques. Recommended for students majoring in health-related sciences. Three class hours, three lab hours.. Prerequisite: BIO152 or BIO115 with a ‘C’ or higher.
Lecture: 3 hrs.
Lab: 3 hrs.
Course Learning Outcomes (CLOs):
Upon successful completion of this course, the student will be able to:
1.Students will identify the methods biological scientists use to explore natural phenomena, including observation, hypothesis development, measurement and data collection, experimentation and the evaluation of data within microbiology as documented by conducting an experiment and writing a formal laboratory report.*
2.Given a case study within a clinical application, students will be able to predict the outcomes of human disease processes within the Respiratory or other system using the principles of microbiology as documented on a written exam.*
3.Name the three domains and the types of organism in each. Explain how organisms are classified and named. List and characterize six types of microorganisms, and explain the roles of microbes in nature and industry.
4.Explain early theories of disease and name and give contributions of important early microbiologists.
5.Describe the structure and function of prokaryotic cells and compare to eukaryotic cells.
6.Identify the basic shapes and arrangements of bacteria. Observe these by use of the microscope and by performing Gram stains, and other staining procedures as assigned in lab. Explain the differences between Gram negative and Gram positive bacteria.
7.List and explain chemical and physical growth requirements of microbes, and describe their growth patterns. Explain the use of different types of media in growing microbes.
8.Describe chemical and physical methods of control of microbial growth, including types and actions of disinfectants. Apply these principles by use of aseptic technique in laboratory exercises.
9.Describe the energy yielding metabolic pathways of microbes, including aerobic and anaerobic pathways.
10.Discuss bacterial genetics including topics such as mutations, plasmids, microbial genetic recombination, DNA replication, protein synthesis, and genetic engineering.
11.Describe the actions and types of antimicrobial drugs. Explain how bacterial resistance develops and give current examples.
12.Define epidemiology and related terminology. Explain and demonstrate in a laboratory experiment how diseases spread. Define nosocomial infections as to definition, types of infections and common microbes involved. Explain the function of the CDC.
13.Describe characteristics that contribute to microbial pathogenicity and virulence including enzymes, toxins, capsules and others. Relate specific virulence factors to specific microbes and the diseases they cause.
14.Describe non-specific (innate) defenses of the body such as inflammation and other chemical and mechanical defenses. Explain specific (acquired) defenses differentiating between humoral and cellular immunity. Distinguish between natural and artificial, active and passive immunity, and describe the primary and secondary immune responses.
15.Investigate, and identify where possible, typical microorganisms found on the human body, and in the respiratory, urinary, and gastrointestinal tracts using laboratory culturing, and identification techniques.
16.Name and describe significant diseases as to diagnosis, pathogenesis, host responses, treatment and prevention based on body systems and/or the major groups of pathogens, including bacteria, fungi, viruses, and others.
* This course objective has been identified as a student learning outcome that must be formally assessed as part of the Comprehensive Assessment Plan of the college. All faculty teaching this course must collect the required data and submit the required analysis and documentation at the conclusion of the semester to the Office of Institutional Research and Assessment.
I. Introduction and History
II. Classification and Survey of Microbes
III. Prokaryotic and Eukaryotic Cell
IV. Microbial Growth, Control of Growth, Antibiotics
V. Microbial Metabolism
VI. Microbial Genetics
VII. Principles of Diseases Epidemiology
VIII. Mechanisms of Pathogenicity
IX. Immunology - Specific and Non Specific
X. Microorganisms and Human Disease
Effective Term: Fall 2016